Sam

Sam is the queen of the Mudokon people, and one of the few female members of the species left alive. She's kept captive in Nolybab, where she is forced to lay her eggs and have her children be born into a life of slavery.

Background
Sam is held captive by the industrial forces of the Magog Cartel and Vykkers labs. Her eggs are shipped off to different industrial corporations under the name of Sam's Labor Eggs to unbeatably hatch into the company's future slave force. Over time, Sam began to enter a deep depression and the Vykkers soon realized that during this depression, Sam produced fewer eggs. So, they used an interrogation robot known as a Shrink (a sentient AI) to keep Sam company and comfort her. It's unknown what her relations or feelings toward her Mudokon offspring are. However, the fact she needs the Shrink to keep her happy implies she would fall into deep depression with the idea of her offspring being taken away into slavery.

It's possible that there used to be plenty of Mudokon females in the past to keep a stable population. It's also likely that she is the only enslaved female, because this makes it easier to control the Mudokon population and ensure that any free Mudokons who oppose the Magog Cartel or Vykker's Conglomerate are the last generation to live, besides the slaves.

Until Sam is rescued, the only way for Mudokons, like Abe, to make sure their kind doesn't die out is with stolen Labor Eggs and rescued scrubs. However in Soulstorm, it is revealed that she gave Abe his stitches.

Behind the Scenes
Sam was originally planned to make an appearance in Munch's Oddysee, being held inside Vykkers Labs. However, due to time constraints, this particular part of the plot was cut, and canonically Sam was not actually on Vykkers labs in the first place. Otherwise, the ending would have meant she most likely died in the subsequent explosion.

She was due to make an appearance in Munch's Exoddus, prior to its cancellation. However, in the good ending of Oddworld: Soulstorm, after learning so much from the Keeper, Abe learns that Sam is now located in Nolybab and has left her kind for unknown reasons.